Difference between revisions of "Articles:Oncological emergencies"

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{{DISPLAYTITLE:Oncological Emergencies}}
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Acute emergencies in oncology are a group of conditions caused by complications of cancer or its treatment, that are life-threatening or irreversibly disabling if clinical management is delayed. As a consequence of our ability to treat increasingly larger numbers of patients effectively, the knowledge to recognise and respond swiftly to such presentations has never been more important.
 
Acute emergencies in oncology are a group of conditions caused by complications of cancer or its treatment, that are life-threatening or irreversibly disabling if clinical management is delayed. As a consequence of our ability to treat increasingly larger numbers of patients effectively, the knowledge to recognise and respond swiftly to such presentations has never been more important.
  
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==Metabolic emergencies==
 
==Metabolic emergencies==
  
* Tumour lysis syndrome
+
*Tumour lysis syndrome
* Hypercalcaemia
+
*Hypercalcaemia
* Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
+
*Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
* Hypomagnesaemia
+
*Hypomagnesaemia
  
 
==Renal & Urological emergencies==
 
==Renal & Urological emergencies==
  
* Obstructive uropathy
+
*Obstructive uropathy
* Urate nephropathy (from TLS)
+
*Urate nephropathy (from TLS)
* Haemorrhagic cystitis<ref>https://www.cancernetwork.com/articles/oncologic-emergencies</ref>
+
*Haemorrhagic cystitis<ref>https://www.cancernetwork.com/articles/oncologic-emergencies</ref>
  
 
==Gastrointestinal emergencies==
 
==Gastrointestinal emergencies==
  
* Obstruction
+
*Obstruction
* Perforation
+
*Perforation
* Gastrointestinal haemorrhage
+
*Gastrointestinal haemorrhage
* Nausea and vomiting (uncontrolled)
+
*Nausea and vomiting (uncontrolled)
* Mucositis (uncontrolled)
+
*Mucositis (uncontrolled)
* Diarrhoea (uncontrolled)
+
*Diarrhoea (uncontrolled)
* Abdominal ascites (malignant)
+
*Abdominal ascites (malignant)
* Neutropaenic enterocolitis
+
*Neutropaenic enterocolitis
  
 
==Neurological emergencies==
 
==Neurological emergencies==
  
* Spinal cord compression
+
*Spinal cord compression
* Cauda equina syndrome
+
*Cauda equina syndrome
* Raised intracranial pressure
+
*Raised intracranial pressure
* Seizures (fits)
+
*Seizures (fits)
  
 
==Haematological emergencies==
 
==Haematological emergencies==
  
* Leukostasis
+
*Leukostasis
* Hyperviscosity
+
*Hyperviscosity
* Disseminated intravascular coagulation
+
*Disseminated intravascular coagulation
* Thrombocytopaenia
+
*Thrombocytopaenia
* Febrile neutropaenia (neutropaenic sepsis)
+
*Febrile neutropaenia (neutropaenic sepsis)
  
 
==Ophthalmological emergencies==
 
==Ophthalmological emergencies==
  
* Ocular and orbital metastases
+
*Ocular and orbital metastases
  
 
==Musculoskeletal emergencies==
 
==Musculoskeletal emergencies==
  
* Metastatic bone pain
+
*Metastatic bone pain
* Pathological fractures
+
*Pathological fractures
  
 
==Gynaecological emergencies==
 
==Gynaecological emergencies==
  
* Gynaecological haemorrhage
+
*Gynaecological haemorrhage
  
 
==Dermatological emergencies==
 
==Dermatological emergencies==
  
* Acute skin reactions
+
*Acute skin reactions
 
<references />
 
<references />

Revision as of 17:53, 29 January 2020


Acute emergencies in oncology are a group of conditions caused by complications of cancer or its treatment, that are life-threatening or irreversibly disabling if clinical management is delayed. As a consequence of our ability to treat increasingly larger numbers of patients effectively, the knowledge to recognise and respond swiftly to such presentations has never been more important.

These emergencies may be encountered at any stage in the pathway of a patient's journey through cancer. This may be at presentation, during the course of treatment, or later in the disease process. Below reviews the most frequently encountered oncological emergencies. It may sound obvious, but it is worth bearing in mind that unrelated acute medical or surgical conditions may occur in patients with malignant disease. Generally, the management will be the same as that of a patient without known cancer.

The emergencies are grouped according to the causative system of origin.

Cardiovascular emergencies

  • Superior vena cava obstruction
  • Cardiac tamponade (malignant pericardial effusion)
  • Venous thromboembolism
  • Extravasation injury
  • Complications of central venous devices[1]

Respiratory emergencies

  • Acute large airway obstruction
  • Pulmonary haemorrhage
  • Respiratory failure
  • Intractable hiccups
  • Radiation pneumonitis
  • Pleural effusion (malignant)

Metabolic emergencies

  • Tumour lysis syndrome
  • Hypercalcaemia
  • Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
  • Hypomagnesaemia

Renal & Urological emergencies

  • Obstructive uropathy
  • Urate nephropathy (from TLS)
  • Haemorrhagic cystitis[2]

Gastrointestinal emergencies

  • Obstruction
  • Perforation
  • Gastrointestinal haemorrhage
  • Nausea and vomiting (uncontrolled)
  • Mucositis (uncontrolled)
  • Diarrhoea (uncontrolled)
  • Abdominal ascites (malignant)
  • Neutropaenic enterocolitis

Neurological emergencies

  • Spinal cord compression
  • Cauda equina syndrome
  • Raised intracranial pressure
  • Seizures (fits)

Haematological emergencies

  • Leukostasis
  • Hyperviscosity
  • Disseminated intravascular coagulation
  • Thrombocytopaenia
  • Febrile neutropaenia (neutropaenic sepsis)

Ophthalmological emergencies

  • Ocular and orbital metastases

Musculoskeletal emergencies

  • Metastatic bone pain
  • Pathological fractures

Gynaecological emergencies

  • Gynaecological haemorrhage

Dermatological emergencies

  • Acute skin reactions